Wrzodek, Clemens and Dräger, Andreas and Zell, Andreas

KEGGtranslator: visualizing and converting the KEGG PATHWAY database to various formats

Bioinformatics vol. 27 (2011), no. 16, pp. 2314-2315


Abstract

Summary: The KEGG PATHWAY database provides a widely used service for metabolic and non-metabolic pathways. It contains manually drawn pathway maps with information about the genes, reactions and relations contained therein. To store these pathways, KEGG uses KGML, a proprietary XML-format. Parsers and translators are needed to process the pathway maps for usage in other applications and algorithms. We have developed KEGGtranslator, an easy-to-use stand-alone application that can visualize and convert KGML formatted XML-files into multiple output formats. Unlike other translators, KEGGtranslator supports a plethora of output formats, is able to augment the information in translated documents (e.g. MIRIAM annotations) beyond the scope of the KGML document, and amends missing components to fragmentary reactions within the pathway to allow simulations on those. Availability: KEGGtranslator is freely available as a Java™ Web Start application and for download at http://www.cogsys.cs.uni-tuebingen.de/software/KEGGtranslator/. KGML files can be downloaded within the application.


Downloads and Links

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BibTeX

@article{Wrzodek2011,
  author = {Wrzodek, Clemens and Dr\"ager, Andreas and Zell, Andreas},
  title = {{KEGGtranslator: visualizing and converting the KEGG PATHWAY database
	to various formats}},
  journal = {Bioinformatics},
  year = {2011},
  volume = {27},
  pages = {2314--2315},
  number = {16},
  month = jun,
  abstract = {Summary: The KEGG PATHWAY database provides a widely used service
	for metabolic and non-metabolic pathways. It contains manually drawn
	pathway maps with information about the genes, reactions and relations
	contained therein. To store these pathways, KEGG uses KGML, a proprietary
	XML-format. Parsers and translators are needed to process the pathway
	maps for usage in other applications and algorithms. We have developed
	KEGGtranslator, an easy-to-use stand-alone application that can visualize
	and convert KGML formatted XML-files into multiple output formats.
	Unlike other translators, KEGGtranslator supports a plethora of output
	formats, is able to augment the information in translated documents
	(e.g. MIRIAM annotations) beyond the scope of the KGML document,
	and amends missing components to fragmentary reactions within the
	pathway to allow simulations on those. Availability: KEGGtranslator
	is freely available as a Java\texttrademark{} Web Start application
	and for download at \url{http://www.cogsys.cs.uni-tuebingen.de/software/KEGGtranslator/}.
	KGML files can be downloaded within the application.},
  doi = {10.1093/bioinformatics/btr377},
  pdf = {http://www.cogsys.cs.uni-tuebingen.de/mitarb/wrzodek/publications/2011-08-04-KEGGtranslator-with-color.pdf},
  url = {http://bioinformatics.oxfordjournals.org/content/27/16/2314}
}